Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 6/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5348722 | 0.98 | — | — | |
| SCHEMBL5351289 | 0.91 | — | — | |
| SCHEMBL735647 | 0.80 | — | — | |
| SCHEMBL2288073 | 0.80 | ALDH1A1 (0.32) | TSHRALDH1A1 | |
| SCHEMBL2278858 | 0.80 | ALDH1A1 (0.32) | TSHRALDH1A1 | |
| SCHEMBL2283394 | 0.80 | ALDH1A1 (0.32) | TSHRALDH1A1 | |
| SCHEMBL2285548 | 0.80 | ALDH1A1 (0.32) | TSHRALDH1A1 | |
| SCHEMBL2285382 | 0.80 | ALDH1A1 (0.32) | TSHRALDH1A1 | |
| SCHEMBL2281979 | 0.80 | ALDH1A1 (0.32) | TSHRALDH1A1 | |
| SCHEMBL2283223 | 0.80 | ALDH1A1 (0.32) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2168952-B1 | MORPHOLINE DERIVATIVES AS RENIN INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2017-02-15 | — | — | EP | disclosed |