Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2813600 | 1.00 | REN (0.51) | RENKCNH2 | |
| SCHEMBL2863009 | 0.87 | REN (0.46) | REN | |
| SCHEMBL13132487 | 0.87 | REN (0.45) | REN | |
| SCHEMBL13132489 | 0.86 | REN (0.51) | REN | |
| SCHEMBL13132471 | 0.84 | REN (0.53) | RENKCNH2 | |
| SCHEMBL13132181 | 0.83 | REN (0.57) | REN | |
| SCHEMBL13132464 | 0.83 | REN (0.57) | RENKCNH2 | |
| SCHEMBL13132183 | 0.81 | REN (0.57) | REN | |
| SCHEMBL13132460 | 0.81 | REN (0.57) | RENKCNH2 | |
| SCHEMBL13132177 | 0.81 | REN (0.57) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2168952-B1 | MORPHOLINE DERIVATIVES AS RENIN INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2017-02-15 | — | — | EP | disclosed |