Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PDE4A | P27815 | 3/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | COMT | P21964 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13168783 | 0.81 | CCNT1 (0.47) | ELANEKDM4EALDH1A1PDE4APDE4B | |
| SCHEMBL30902715 | 0.79 | ELANE (0.40) | ELANEKDM4EALDH1A1PDE4APDE4B | |
| SCHEMBL29223650 | 0.79 | ELANE (0.40) | ELANEKDM4EALDH1A1PDE4APDE4B | |
| SCHEMBL12146938 | 0.79 | ELANE (0.40) | ELANEKDM4EALDH1A1PDE4APDE4B | |
| SCHEMBL3210383 | 0.79 | ELANE (0.40) | ELANEKDM4EALDH1A1PDE4APDE4B | |
| SCHEMBL18993226 | 0.78 | PDE4A (0.42) | ELANEKDM4EALDH1A1PDE4APDE4B | |
| SCHEMBL21285314 | 0.74 | HTR6 (0.46) | ELANEHTR6 | |
| SCHEMBL22252332 | 0.74 | CNR2 (0.53) | ELANEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4569768 | 0.74 | FEN1 (0.40) | ELANEKDM4EALDH1A1FEN1HTR6 | |
| SCHEMBL3210378 | 0.74 | PARP1 (0.49) | ELANEFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2168952-B1 | MORPHOLINE DERIVATIVES AS RENIN INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2017-02-15 | — | — | EP | disclosed |