Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 12/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | GFER | P55789 | 2/20 | 0.50 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.47 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.47 |
| ▸ | GRK6 | P43250 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4434581 | 0.82 | ALDH1A1 (0.54) | CNR2ALDH1A1TSHRGFERPSMD14 | |
| SCHEMBL12000833 | 0.82 | ALDH1A1 (0.54) | CNR2ALDH1A1TSHRGFERPSMD14 | |
| SCHEMBL10080950 | 0.82 | ALDH1A1 (0.60) | CNR2ALDH1A1TSHRGFERPSMD14 | |
| SCHEMBL667861 | 0.80 | ALDH1A1 (0.52) | CNR2ALDH1A1TSHRGFERPSMD14 | |
| SCHEMBL131813 | 0.79 | ALDH1A1 (0.56) | CNR2ALDH1A1TSHRGFERPSMD14 | |
| SCHEMBL17428470 | 0.78 | CNR2 (0.50) | CNR2ALDH1A1TSHRGFERPSMD14 | |
| SCHEMBL14308404 | 0.78 | CNR2 (0.50) | CNR2ALDH1A1TSHRGFERPSMD14 | |
| SCHEMBL11107464 | 0.78 | CNR2 (0.50) | CNR2ALDH1A1TSHRGFERPSMD14 | |
| SCHEMBL9158083 | 0.78 | ALDH1A1 (0.55) | CNR2ALDH1A1TSHRGFERPSMD14 | |
| SCHEMBL11478859 | 0.78 | ALDH1A1 (0.56) | CNR2ALDH1A1TSHRGFERPSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170042905-A1 | Prostaglandin Receptor EP2 Antagonists, Derivatives, Compositions, and Uses Related Thereto | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170042905-A1 | Prostaglandin Receptor EP2 Antagonists, Derivatives, Compositions, and Uses Related Thereto | PTGER2, PTGES2, PTGER1 | CNR2 18/4885ALDH1A1 1095/4885TSHR 1264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.