Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822779 | 0.89 | TDP1 (0.72) | TDP1ALDH1A1MAPTCYP2A6KDM4E | |
| SCHEMBL18511351 | 0.86 | TDP1 (0.80) | TDP1ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL13754210 | 0.81 | TDP1 (0.57) | TDP1ALDH1A1MAPTCYP2A6KDM4E | |
| SCHEMBL30134116 | 0.79 | TDP1 (0.54) | TDP1ALDH1A1MAPTCYP2A6KDM4E | |
| SCHEMBL26260604 | 0.79 | NPC1 (0.62) | TDP1ALDH1A1MAPTHPGDNPC1 | |
| SCHEMBL9091793 | 0.77 | TDP1 (0.50) | TDP1ALDH1A1MAPTCYP2A6KDM4E | |
| SCHEMBL31133324 | 0.74 | TDP1 (1.00) | TDP1ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL4348032 | 0.74 | TDP1 (1.00) | TDP1ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL9822932 | 0.74 | CYP2A6 (0.49) | TDP1ALDH1A1MAPTCYP2A6KDM4E | |
| SCHEMBL9823025 | 0.74 | NPC1 (0.75) | TDP1ALDH1A1MAPTHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240300951-A1 | Pyrazolopyridinone Compounds | BEIGENE LTD. (KY) | 2024-09-12 | — | — | US | disclosed |
| US-20240270751-A1 | Pyrazolopyridinone Compounds | BEIGENE LTD. (KY) | 2024-08-15 | — | — | US | disclosed |
| CN-117836296-A | Pyrazolopyridone compounds | 百济神州有限公司 | 2024-04-05 | — | — | CN | disclosed |
| WO-2023173026-A1 | ANTIBODY-DRUG CONJUGATES AND USES THEREOF | SORRENTO THERAPEUTICS, INC. (US) | 2023-09-14 | — | — | WO | disclosed |
| US-20170047592-A1 | MOLECULARLY TUNABLE HETEROGENEOUS CATALYSTS BY EDGE FUNCTIONALIZATION OF GRAPHITIC CARBONS | UNITED STATES DEPARTMENT OF ENERGY | 2017-02-16 | — | — | US | disclosed |
| US-9540765-B2 | Mixtures of reactive dyes and their use in a method of di- or trichromatic dyeing or printing | HUNTSMAN INTERNATIONAL LLC (US) | 2017-01-10 | — | — | US | disclosed |
| US-9346958-B2 | Reactive dyes, their preparation and their use | HUNTSMAN INTERNATIONAL LLC (US) | 2016-05-24 | — | — | US | disclosed |
| US-20150354134-A1 | Mixtures of Reactive Dyes and Their Use in a Method of Di- or Trichromatic Dyeing or Printing | HUNTSMAN INTERNATIONAL LLC | 2015-12-10 | — | — | US | disclosed |
| US-20150143639-A1 | Reactive Dyes, Their Preparation and Their Use | HUNTSMAN INTERNATIONAL LLC | 2015-05-28 | — | — | US | disclosed |
| US-8348412-B2 | Reactive dyes, their preparation and their use | HUNTSMAN INTERNATIONAL LLC (US) | 2013-01-08 | — | — | US | disclosed |
| US-20110285781-A1 | REACTIVE DYES, THEIR PREPARATION AND THEIR USE | HUNTSMAN INTERNATIONAL LLC (US) | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170047592-A1 | MOLECULARLY TUNABLE HETEROGENEOUS CATALYSTS BY EDGE FUNCTIONALIZATION OF GRAPHITIC CARBONS | APEX1, SCO2, EHMT2 | TDP1 2009/4885ALDH1A1 2305/4885MAPT 2439/4885 |
| US-20150143639-A1 | Reactive Dyes, Their Preparation and Their Use | H1-2, H1-3, H1-4 | TDP1 2847/4885ALDH1A1 1621/4885MAPT 2575/4885 |
| US-20240300951-A1 | Pyrazolopyridinone Compounds | NFATC1, CD4, PBK | TDP1 959/4885ALDH1A1 1296/4885MAPT 4030/4885 |
| US-20240270751-A1 | Pyrazolopyridinone Compounds | NFATC1, CD4, PBK | TDP1 959/4885ALDH1A1 1296/4885MAPT 4030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.