Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9823025 | 0.90 | NPC1 (0.75) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL9822779 | 0.85 | TDP1 (0.72) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL16644147 | 0.79 | NPC1 (0.55) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL24920215 | 0.79 | NPC1 (0.54) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL18511345 | 0.79 | TDP1 (0.59) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL13754210 | 0.78 | TDP1 (0.57) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL9822885 | 0.77 | NPC1 (0.53) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL11421185 | 0.76 | NQO2 (0.53) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL24920314 | 0.76 | NPC1 (0.51) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL26261541 | 0.76 | NPC1 (0.73) | NPC1RAB9AMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023173026-A1 | ANTIBODY-DRUG CONJUGATES AND USES THEREOF | SORRENTO THERAPEUTICS, INC. (US) | 2023-09-14 | — | — | WO | disclosed |