Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 11/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.49 |
| ▸ | MYC | P01106 | 1/20 | 0.48 |
| ▸ | CLK1 | P49759 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24329695 | 0.81 | RAB9A (0.60) | POLBNPC1MEN1KMT2ARAB9A | |
| SCHEMBL14549191 | 0.78 | POLB (0.68) | POLBNPC1MEN1KMT2ARAB9A | |
| SCHEMBL26603055 | 0.77 | POLB (0.48) | POLBNPC1MEN1KMT2ARAB9A | |
| Hydrochloric Acid SCHEMBL31194825 | 0.77 | POLB (0.66) | POLBNPC1MEN1KMT2ARAB9A | |
| SCHEMBL12030352 | 0.76 | MAPT (0.59) | POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5740431 | 0.76 | RAB9A (0.70) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL12442963 | 0.76 | DYRK1A (0.57) | DYRK1AADORA1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3283083 | 0.76 | DYRK1A (1.00) | DYRK1AADORA1NPC1MEN1KMT2A | |
| SCHEMBL24329369 | 0.76 | NPC1 (0.53) | POLBNPC1MEN1KMT2ARAB9A | |
| SCHEMBL1558460 | 0.75 | DYRK1A (0.58) | DYRK1AADORA1POLBNPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402327-A1 | Acetamide compounds as glucokinase activators, their process and medicinal applications | Advinus Therapeutics Private Limited (IN) | 2012-01-04 | — | — | EP | claimed |