Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 5/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3217605 | 0.96 | GPR52 (0.47) | GPR52TP53POLBHPGDRAB9A | |
| SCHEMBL1864780 | 0.93 | GPR52 (0.50) | GPR52CYP4F2CYP4A11TP53POLB | |
| SCHEMBL1851227 | 0.92 | GPR52 (0.44) | GPR52TP53POLBHPGDRAB9A | |
| SCHEMBL3206666 | 0.89 | GPR52 (0.54) | GPR52CYP4F2CYP4A11TP53POLB | |
| SCHEMBL1854682 | 0.89 | TP53 (0.43) | CYP4F2CYP4A11TP53POLBHPGD | |
| SCHEMBL1850740 | 0.87 | GPR52 (0.49) | GPR52TP53POLBHPGDRAB9A | |
| SCHEMBL1854655 | 0.85 | GPR52 (0.51) | GPR52CYP4F2CYP4A11TP53POLB | |
| SCHEMBL1854211 | 0.85 | TP53 (0.41) | CYP4F2CYP4A11TP53POLBHPGD | |
| SCHEMBL1852550 | 0.85 | GPR52 (0.46) | GPR52CYP4F2CYP4A11TP53POLB | |
| SCHEMBL1851960 | 0.84 | GPR52 (0.55) | GPR52TP53POLBHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |