Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18518987 | 1.00 | TSPO (0.35) | TSPOKDM4EATML3MBTL1PDK2 | |
| SCHEMBL18518701 | 0.98 | KDM4E (0.38) | TSPOKDM4EATML3MBTL1PDK2 | |
| SCHEMBL15946323 | 0.98 | TSPO (0.35) | TSPOKDM4EATML3MBTL1PDK2 | |
| SCHEMBL18518986 | 0.98 | TSPO (0.37) | TSPOKDM4EATML3MBTL1PDK2 | |
| SCHEMBL18518227 | 0.96 | KDM4E (0.38) | TSPOKDM4EATML3MBTL1PDK2 | |
| SCHEMBL18518165 | 0.96 | KDM4E (0.38) | TSPOKDM4EATML3MBTL1PDK2 | |
| SCHEMBL18518999 | 0.96 | KDM4E (0.38) | TSPOKDM4EATML3MBTL1PDK2 | |
| SCHEMBL18518994 | 0.96 | KDM4E (0.38) | TSPOKDM4EATML3MBTL1PDK2 | |
| SCHEMBL14822631 | 0.96 | KDM4E (0.38) | TSPOKDM4EATML3MBTL1PDK2 | |
| SCHEMBL18518075 | 0.96 | KDM4E (0.40) | TSPOKDM4EATML3MBTL1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3335254-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-04-08 | — | — | EP | disclosed |
| WO-2017025164-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-02-16 | — | — | WO | disclosed |