Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | LSS | P48449 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5045619 | 0.89 | MLYCD (0.53) | MLYCDTMEM97SIGMAR1LSSL3MBTL1 | |
| SCHEMBL1854991 | 0.85 | TMEM97 (0.50) | MLYCDTMEM97SIGMAR1LSSL3MBTL1 | |
| SCHEMBL1852887 | 0.85 | TMEM97 (0.50) | MLYCDTMEM97SIGMAR1LSSL3MBTL1 | |
| SCHEMBL6718419 | 0.84 | MLYCD (0.60) | MLYCDTMEM97SIGMAR1LSSL3MBTL1 | |
| SCHEMBL1851511 | 0.82 | MLYCD (0.46) | MLYCDTMEM97SIGMAR1LSSL3MBTL1 | |
| SCHEMBL1853956 | 0.82 | MLYCD (0.46) | MLYCDTMEM97SIGMAR1LSSL3MBTL1 | |
| Water SCHEMBL27619618 | 0.82 | MLYCD (0.50) | MLYCDTMEM97SIGMAR1LSSL3MBTL1 | |
| SCHEMBL1852987 | 0.81 | TMEM97 (0.56) | MLYCDTMEM97SIGMAR1LSSL3MBTL1 | |
| SCHEMBL6717461 | 0.81 | MLYCD (0.56) | MLYCDTMEM97SIGMAR1LSSL3MBTL1 | |
| SCHEMBL1853427 | 0.81 | TMEM97 (0.56) | MLYCDTMEM97SIGMAR1LSSL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470102-B1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | MERCK SERONO SA (CH) | 2011-05-25 | — | — | EP | disclosed |