Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 6/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 2/20 | 0.43 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CSK | P41240 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.43 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.43 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.43 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1847687 | 0.82 | CMA1 (0.64) | CMA1LMNATSHR | |
| SCHEMBL6115028 | 0.75 | CMA1 (1.00) | CMA1LMNAHPGDTSHR | |
| SCHEMBL6115916 | 0.73 | CMA1 (0.81) | CMA1SMN1; SMN2P2RX3LMNAHPGD | |
| SCHEMBL6115031 | 0.72 | CMA1 (0.61) | CMA1SMN1; SMN2P2RX3LMNAHPGD | |
| SCHEMBL18900851 | 0.72 | CMA1 (0.72) | CMA1SMN1; SMN2LMNAHPGDTSHR | |
| SCHEMBL7960570 | 0.71 | CMA1 (1.00) | CMA1SMN1; SMN2SRCABL1P2RX3 | |
| SCHEMBL1851671 | 0.70 | CMA1 (1.00) | CMA1SMN1; SMN2SRCABL1P2RX3 | |
| SCHEMBL18900937 | 0.70 | CMA1 (0.73) | CMA1SMN1; SMN2SRCABL1P2RX3 | |
| SCHEMBL7962647 | 0.70 | CMA1 (0.78) | CMA1SMN1; SMN2SRCABL1P2RX3 | |
| SCHEMBL7963507 | 0.69 | CMA1 (0.73) | CMA1SMN1; SMN2LMNAHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323991-A2 | CHYMASE INHIBITORS | Boehringer Ingelheim International GmbH (DE) | 2011-05-25 | — | — | EP | disclosed |