Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 18/20 | 0.89 |
| ▸ | F11 | P03951 | 17/20 | 0.80 |
| ▸ | F9 | P00740 | 14/20 | 0.72 |
| ▸ | F12 | P00748 | 1/20 | 0.70 |
| ▸ | PLAT | P00750 | 1/20 | 0.70 |
| ▸ | PROC | P04070 | 1/20 | 0.70 |
| ▸ | F7 | P08709 | 1/20 | 0.70 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.70 |
| ▸ | CTRL | P40313 | 1/20 | 0.70 |
| ▸ | CTRB2 | Q6GPI1 | 1/20 | 0.70 |
| ▸ | CTRC | Q99895 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15594151 | 0.94 | KLKB1 (1.00) | KLKB1F11F9F12PLAT | |
| SCHEMBL18124030 | 0.94 | KLKB1 (0.89) | KLKB1F11F9F12PLAT | |
| SCHEMBL15456817 | 0.89 | KLKB1 (1.00) | KLKB1F11F9F12PLAT | |
| SCHEMBL18123972 | 0.88 | F11 (0.91) | KLKB1F11F9F12PLAT | |
| SCHEMBL18523900 | 0.88 | KLKB1 (0.90) | KLKB1F11F9F12PLAT | |
| SCHEMBL16910511 | 0.88 | F11 (0.91) | KLKB1F11F9F12PLAT | |
| SCHEMBL18523795 | 0.88 | F11 (0.90) | KLKB1F11F9F12PLAT | |
| SCHEMBL18124051 | 0.88 | F11 (0.91) | KLKB1F11F9F12PLAT | |
| SCHEMBL17991856 | 0.88 | KLKB1 (1.00) | KLKB1F11F9F12PLAT | |
| SCHEMBL18124007 | 0.88 | F11 (0.91) | KLKB1F11F9F12PLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2880026-B1 | DIHYDROPYRIDONE P1 AS FACTOR XIA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-02-22 | — | — | EP | claimed |