Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 10/20 | 0.68 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | PTPN9 | P43378 | 1/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1849964 | 0.94 | GPR52 (0.75) | GPR52NR4A2MRGPRX4KDM4EMEN1 | |
| SCHEMBL1850184 | 0.83 | GPR52 (0.60) | GPR52NR4A2MRGPRX4KDM4EMEN1 | |
| SCHEMBL1847848 | 0.83 | GPR52 (0.51) | GPR52 | |
| SCHEMBL1854347 | 0.81 | GPR52 (0.56) | GPR52NR4A2MRGPRX4PTGER1PLA2G2A | |
| SCHEMBL1849703 | 0.81 | GPR52 (0.57) | GPR52NR4A2MRGPRX4KDM4EMEN1 | |
| SCHEMBL1851771 | 0.81 | GPR52 (1.00) | GPR52MRGPRX4 | |
| SCHEMBL3209952 | 0.80 | GPR52 (0.76) | GPR52MRGPRX4ALDH1A1 | |
| SCHEMBL3212711 | 0.80 | GPR52 (0.55) | GPR52NR4A2PTGER1PLA2G2A | |
| SCHEMBL1851338 | 0.79 | GPR52 (0.69) | GPR52NR4A2MRGPRX4PTGER1 | |
| SCHEMBL1850535 | 0.79 | GPR52 (0.55) | GPR52NR4A2MRGPRX4KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |