Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1355333 | 1.00 | SYK (0.60) | SYKCAMK1D | |
| SCHEMBL1852551 | 0.90 | SYK (0.61) | SYKCAMK1D | |
| SCHEMBL1847521 | 0.88 | SYK (0.62) | SYKCAMK1D | |
| SCHEMBL1355070 | 0.88 | SYK (0.62) | SYKCAMK1D | |
| SCHEMBL1849685 | 0.87 | SYK (0.59) | SYKCAMK1D | |
| SCHEMBL1354628 | 0.87 | SYK (0.59) | SYKCAMK1D | |
| SCHEMBL1853033 | 0.85 | SYK (0.61) | SYK | |
| SCHEMBL1352375 | 0.85 | SYK (0.61) | SYK | |
| SCHEMBL1353406 | 0.85 | SYK (0.61) | SYKCAMK1D | |
| SCHEMBL1354029 | 0.85 | SYK (0.64) | SYKCAMK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323993-A2 | 2,6-DIAMINO- PYRIMIDIN- 5-YL-CARBOXAMIDES AS SYK OR JAK KINASES INHIBITORS | Portola Pharmaceuticals, Inc. (US) | 2011-05-25 | — | — | EP | disclosed |
| WO-2009136995-A2 | INHIBITORS OF SYK PROTEIN KINASE | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-12 | — | — | WO | disclosed |