Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 6/20 | 0.70 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.47 |
| ▸ | FYN | P06241 | 4/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3217594 | 0.96 | GPR52 (0.75) | GPR52PTGER4FYNADORA3ADORA2B | |
| SCHEMBL1851055 | 0.91 | GPR52 (0.65) | GPR52PTGER4FYNADORA3ADORA2B | |
| SCHEMBL3206799 | 0.90 | GPR52 (0.78) | GPR52FYNADORA3ADORA2BHDAC6 | |
| SCHEMBL1850248 | 0.90 | GPR52 (0.54) | GPR52PTGER4ADORA3ADORA2BHDAC6 | |
| SCHEMBL1853937 | 0.89 | GPR52 (0.72) | GPR52PTGER4FYNADORA3ADORA2B | |
| SCHEMBL1849152 | 0.88 | GPR52 (0.79) | GPR52PTGER4FYN | |
| SCHEMBL3207391 | 0.88 | GPR52 (0.75) | GPR52PTGER4FYN | |
| SCHEMBL1850562 | 0.87 | GPR52 (0.72) | GPR52PTGER4FYNADORA3ADORA2B | |
| SCHEMBL3209129 | 0.87 | GPR52 (0.69) | GPR52FYNADORA3ADORA2B | |
| SCHEMBL1849610 | 0.86 | GPR52 (0.93) | GPR52PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |