Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.34 |
| ▸ | CTSS | P25774 | 2/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.33 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.31 |
| ▸ | CHRNG | P07510 | 1/20 | 0.31 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.31 |
| ▸ | CHRND | Q07001 | 1/20 | 0.31 |
| ▸ | CHRNA2 | Q15822 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18489390 | 0.83 | CTSK (0.43) | CTSKCTSSHRH4DRD2DRD3 | |
| SCHEMBL18489380 | 0.79 | CTSK (0.47) | CTSKCTSSHRH4 | |
| SCHEMBL18489386 | 0.75 | CTSK (0.39) | CTSKCTSS | |
| SCHEMBL3720436 | 0.74 | CYP1A1 (0.39) | — | |
| SCHEMBL12250775 | 0.72 | HRH4 (0.42) | CTSKCTSSHRH4TLR8 | |
| SCHEMBL19531941 | 0.69 | HRH4 (0.40) | CTSKCTSSHRH4TLR8 | |
| Hydrochloric Acid SCHEMBL28371163 | 0.69 | HRH4 (0.36) | CTSKCTSSHRH4 | |
| SCHEMBL18497852 | 0.69 | RAMP1 (0.38) | CTSKCTSSHRH4TLR8 | |
| SCHEMBL25406682 | 0.68 | TLR8 (0.41) | TLR8 | |
| Hydrochloric Acid SCHEMBL18489419 | 0.68 | RAMP1 (0.37) | CTSKCTSSHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017027343-A1 | CGRP RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2017-02-16 | — | — | WO | disclosed |