Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26159879 | 0.88 | DPP4 (0.44) | ALDH1A1LMNACA12CA1CA2 | |
| SCHEMBL13612864 | 0.81 | MEN1 (0.47) | ALDH1A1LMNACA12CA1CA2 | |
| SCHEMBL10305072 | 0.81 | MEN1 (0.47) | ALDH1A1LMNACA12CA1CA2 | |
| SCHEMBL10305071 | 0.81 | MEN1 (0.47) | ALDH1A1LMNACA12CA1CA2 | |
| SCHEMBL15808644 | 0.81 | CA12 (0.47) | ALDH1A1LMNACA12CA1CA2 | |
| SCHEMBL14311859 | 0.81 | CA12 (0.47) | ALDH1A1LMNACA12CA1CA2 | |
| SCHEMBL15808575 | 0.81 | CA12 (0.47) | ALDH1A1LMNACA12CA1CA2 | |
| SCHEMBL13194848 | 0.79 | — | — | |
| SCHEMBL6997588 | 0.78 | GAA (0.46) | ALDH1A1LMNACA12CA1CA2 | |
| SCHEMBL2414532 | 0.78 | ALDH1A1 (0.45) | ALDH1A1LMNACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017025849-A1 | BICYCLIC-FUSED HETEROARYL OR ARYL COMPOUNDS | PFIZER INC. (US) | 2017-02-16 | — | — | WO | disclosed |