SCHEMBL18525840

SCHEMBL18525840

COC(=O)c1ccc(C2=CC[C@@]3(C)C(CC[C@]4(C)C3CC[C@@H]3C5[C@H](C6(C)CC6)CC[C@]5(C(=O)O)CC[C@]34C)C2(C)C)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15947500 1.00
SCHEMBL15918674 1.00
SCHEMBL15917515 0.92
SCHEMBL15933732 0.90
SCHEMBL9110970 0.89 GPBAR1 (0.53)
SCHEMBL15916808 0.88
SCHEMBL18525879 0.88 GPBAR1 (0.60)
SCHEMBL9104978 0.88 GPBAR1 (0.60)
SCHEMBL9110443 0.88 GPBAR1 (0.60)
SCHEMBL12698045 0.88 GPBAR1 (0.60)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017025901-A1 NOVEL C28-ANALOGUES WITH C3-MODIFICATIONS OF TRITERPENE DERIVATIVES AS HIV INHIBITORS HETERO RESEARCH FOUNDATION (IN) 2017-02-16 WO disclosed