SCHEMBL185267

SCHEMBL185267

COC(=O)[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LGALS3 P17931 1/20 0.44
CA1 P00915 5/20 0.41
CA2 P00918 5/20 0.41
CA9 Q16790 5/20 0.41
PYGB P11216 1/20 0.37
AHCY P23526 1/20 0.37
CYP2C19 P33261 1/20 0.35
CA12 O43570 3/20 0.33
PPM1B O75688 1/20 0.33
PTPN1 P18031 1/20 0.33
PPP1CC P36873 1/20 0.33
CDK1 P06493 1/20 0.33
CCNB1 P14635 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
ITGA4 P13612 1/20 0.33
CA14 Q9ULX7 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4107459 1.00 LGALS3 (0.44) LGALS3CA1CA2CA9PYGB
SCHEMBL4096725 1.00 LGALS3 (0.44) LGALS3CA1CA2CA9PYGB
SCHEMBL30353978 1.00 LGALS3 (0.44) LGALS3CA1CA2CA9PYGB
SCHEMBL26243844 1.00 LGALS3 (0.44) LGALS3CA1CA2CA9PYGB
SCHEMBL12085049 1.00 LGALS3 (0.44) LGALS3CA1CA2CA9PYGB
SCHEMBL1811839 1.00 LGALS3 (0.44) LGALS3CA1CA2CA9PYGB
SCHEMBL30660898 1.00 LGALS3 (0.44) LGALS3CA1CA2CA9PYGB
SCHEMBL12082047 1.00 LGALS3 (0.44) LGALS3CA1CA2CA9PYGB
SCHEMBL7154268 1.00 LGALS3 (0.44) LGALS3CA1CA2CA9PYGB
SCHEMBL29065825 0.98 LGALS3 (0.43) LGALS3CA1CA2CA9PYGB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115368300-B Compound for TLR8 inhibitor and preparation method and application thereof 北京拓领博泰生物科技有限公司 2023-03-24 CN claimed
CN-115819391-A Baicalein derivative, preparation method and application thereof 中国科学院上海药物研究所 2023-03-21 CN claimed
CN-115368300-A Compound for TLR8 inhibitor and preparation method and application thereof 北京拓领博泰生物科技有限公司 2022-11-22 CN claimed
CN-116981679-A Selective estrogen receptor degrading agent 伊莱利利公司 2023-10-31 CN disclosed
CN-115368300-B Compound for TLR8 inhibitor and preparation method and application thereof 北京拓领博泰生物科技有限公司 2023-03-24 CN disclosed
CN-115819391-A Baicalein derivative, preparation method and application thereof 中国科学院上海药物研究所 2023-03-21 CN disclosed
CN-112110978-B Delta-oleanolic acid saponin compound and medical application thereof 中国药科大学 2023-02-28 CN disclosed
CN-115368300-A Compound for TLR8 inhibitor and preparation method and application thereof 北京拓领博泰生物科技有限公司 2022-11-22 CN disclosed
CN-115298171-A Method for producing epigallocatechin gallate conjugate 花王株式会社 2022-11-04 CN disclosed
EP-2402762-B1 Chloral hydrate immunoassay RANDOX LAB LTD (GB) 2013-05-08 EP disclosed
EP-2402762-A1 Chloral hydrate immunoassay Randox Laboratories Ltd. (GB) 2012-01-04 EP disclosed
EP-2402761-A1 Chloral hydrate detection Randox Laboratories Ltd. (GB) 2012-01-04 EP disclosed