Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4440119 | 0.91 | KMT2A (0.62) | ATML3MBTL1KMT2AMEN1TDP1 | |
| SCHEMBL10404896 | 0.88 | ATM (0.58) | ATML3MBTL1KMT2AMEN1TDP1 | |
| SCHEMBL12518836 | 0.86 | HPGD (0.58) | ATML3MBTL1KMT2AMEN1TDP1 | |
| SCHEMBL27294527 | 0.85 | ATM (0.45) | ATML3MBTL1KMT2AMEN1TDP1 | |
| SCHEMBL12282233 | 0.85 | KMT2A (0.52) | ATML3MBTL1KMT2AMEN1TDP1 | |
| SCHEMBL4297608 | 0.83 | GNAI3 (0.44) | ATML3MBTL1KMT2AMEN1TDP1 | |
| SCHEMBL22336795 | 0.83 | ATM (0.53) | ATML3MBTL1KMT2AMEN1TDP1 | |
| SCHEMBL2606049 | 0.82 | NPC1 (0.73) | ATMKMT2AMEN1HPGDRAB9A | |
| SCHEMBL13535832 | 0.80 | ATM (0.41) | ATML3MBTL1KMT2AMEN1TDP1 | |
| SCHEMBL25030390 | 0.79 | HPGD (0.53) | ATML3MBTL1KMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023002165-A1 | INHIBITOR COMPOUNDS | Neophore Limited (GB) | 2023-01-26 | — | — | WO | disclosed |
| EP-2499132-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-02-15 | — | — | EP | disclosed |