Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 10/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 8/20 | 0.42 |
| ▸ | TUBB | P07437 | 8/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 8/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 8/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 8/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 8/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 8/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 8/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 8/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 8/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 8/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17224294 | 1.00 | PTGS1 (0.47) | PTGS1MEN1NPC1HSP90AA1GAA | |
| SCHEMBL17224330 | 0.94 | PTGS1 (0.47) | PTGS1MEN1NPC1HSP90AA1GAA | |
| SCHEMBL17224331 | 0.94 | PTGS1 (0.47) | PTGS1MEN1NPC1HSP90AA1GAA | |
| SCHEMBL17224381 | 0.90 | PTGS1 (0.51) | PTGS1MEN1NPC1HSP90AA1GAA | |
| SCHEMBL17224380 | 0.90 | PTGS1 (0.51) | PTGS1MEN1NPC1HSP90AA1GAA | |
| SCHEMBL18540717 | 0.87 | PTGS1 (0.59) | PTGS1MEN1NPC1HSP90AA1GAA | |
| SCHEMBL17224400 | 0.87 | PTGS1 (0.59) | PTGS1MEN1NPC1HSP90AA1GAA | |
| SCHEMBL17224345 | 0.87 | PTGS1 (0.59) | PTGS1MEN1NPC1HSP90AA1GAA | |
| SCHEMBL17224365 | 0.81 | INPPL1 (0.36) | PTGS1MEN1NPC1HSP90AA1GAA | |
| SCHEMBL17224367 | 0.81 | INPPL1 (0.36) | PTGS1MEN1NPC1HSP90AA1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170051149-A1 | AZOARYLS AS REVERSIBLY MODULATABLE TUBULIN INHIBITORS | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2017-02-23 | — | — | US | claimed |
| US-20170051149-A1 | AZOARYLS AS REVERSIBLY MODULATABLE TUBULIN INHIBITORS | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2017-02-23 | — | — | US | disclosed |