Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | APEX1 | P27695 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 3/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.34 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21981937 | 0.74 | KMT2A (0.52) | KMT2AKDM4EAPEX1DAOHCAR2 | |
| SCHEMBL700764 | 0.74 | APEX1 (0.55) | KMT2AKDM4EAPEX1DAOHCAR2 | |
| SCHEMBL6626531 | 0.73 | — | — | |
| SCHEMBL28227106 | 0.73 | KDM4E (0.39) | KMT2AKDM4EDAOALDH1A1HPGD | |
| SCHEMBL28443819 | 0.72 | KMT2A (0.57) | KMT2AKDM4EAPEX1DAOHCAR2 | |
| SCHEMBL528110 | 0.72 | — | — | |
| SCHEMBL14619933 | 0.71 | KMT2A (0.48) | KMT2AKDM4EAPEX1DAOHCAR2 | |
| SCHEMBL4379207 | 0.71 | KDM4E (0.48) | KMT2AKDM4EAPEX1DAOHCAR2 | |
| SCHEMBL20582083 | 0.71 | KMT2A (0.48) | KMT2AKDM4EAPEX1DAOHCAR2 | |
| SCHEMBL19406488 | 0.69 | APEX1 (0.39) | KMT2AKDM4EAPEX1DAOALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10087161-B2 | Synthesis of FDCA and FDCA precursors from gluconic acid derivatives | SYNTHETIC GENOMICS, INC. (US) | 2018-10-02 | — | — | US | disclosed |
| US-20170050944-A1 | SYNTHESIS OF FDCA AND FDCA PRECURSORS FROM GLUCONIC ACID DERIVATIVES | VIRIDOS, INC. | 2017-02-23 | — | — | US | disclosed |
| WO-2017030668-A1 | SYNTHESIS OF FDCA AND FDCA PRECURSORS FROM GLUCONIC ACID DERIVATIVES | SYNTHETIC GENOMICS, INC. (US) | 2017-02-23 | — | — | WO | disclosed |