Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18529139 | 1.00 | KCNH2 (0.46) | KCNH2 | |
| SCHEMBL18529122 | 0.91 | KCNH2 (0.40) | KCNH2 | |
| SCHEMBL20679420 | 0.91 | KCNH2 (0.40) | KCNH2 | |
| SCHEMBL18529028 | 0.90 | KCNH2 (0.42) | KCNH2 | |
| SCHEMBL20679469 | 0.90 | KCNH2 (0.42) | KCNH2 | |
| SCHEMBL20679422 | 0.89 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL20679509 | 0.88 | MTNR1A (0.43) | KCNH2 | |
| SCHEMBL20679189 | 0.87 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL18529179 | 0.87 | KCNH2 (0.56) | KCNH2 | |
| SCHEMBL18529182 | 0.87 | KCNH2 (0.56) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3334739-A2 | ANTIBACTERIAL AGENTS COMPRISING A PYRAZINO[2,3-B][1,4]OXAZIN-3-ONE OR A RELATED RING SYSTEM | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2018-06-20 | — | — | EP | claimed |
| WO-2017029602-A2 | COMPOUNDS FOR USE IN ANTIBACTERIAL APPLICATIONS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-02-23 | — | — | WO | claimed |