SCHEMBL1852952

SCHEMBL1852952

O=Nc1ncc[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11103862 0.80 MEN1 (0.52)
SCHEMBL11107953 0.80 MEN1 (0.52)
SCHEMBL5487957 0.80 MEN1 (0.52)
SCHEMBL4298276 0.78 ALDH1A1 (0.43)
Hydrochloric Acid SCHEMBL28371398 0.78 MEN1 (0.50)
Benzene SCHEMBL28173940 0.76 MEN1 (0.48)
SCHEMBL11700080 0.74
SCHEMBL183872 0.74
SCHEMBL17623356 0.74
SCHEMBL1752174 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107519840-A Carrying methods and silicon matrix material and application of a kind of ZIFs on silicon matrix 中国科学院大连化学物理研究所 2017-12-29 CN claimed
US-4251320-A Method of producing a mineral fiber product ROCKWOOL AKTIEBOLAG (SE) 1981-02-17 US claimed
US-20240226114-A1 INHIBITORS AND USES THEREOF VIVIDION THERAPEUTICS, INC. 2024-07-11 US disclosed
CN-113493458-B Preparation method of temozolomide 鲁南制药集团股份有限公司 2024-03-15 CN disclosed
CN-113493418-B Temozolomide intermediate compound IV 鲁南制药集团股份有限公司 2024-03-15 CN disclosed
US-20230303570-A1 KINASE INHIBITORS AND USES THEREOF ABM THERAPEUTICS CORP (US) 2023-09-28 US disclosed
US-20230158177-A1 HYPOXIA-TARGETING CONTRAST AGENT AND METHODS OF USE THEREOF ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2023-05-25 US disclosed
US-20230158177-A1 HYPOXIA-TARGETING CONTRAST AGENT AND METHODS OF USE THEREOF ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2023-05-25 US disclosed
US-20230071620-A1 PHARMACEUTICAL COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS ACHILLION PHARMACEUTICALS, INC. 2023-03-09 US disclosed
US-20230055237-A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS FLATLEY DISCOVERY LAB, LLC 2023-02-23 US disclosed
US-11247988-B2 RAD51 inhibitors CYTEIR THERAPEUTICS, INC. (US) 2022-02-15 US disclosed
US-20080200689-A1 1-Substituted-4-nitroimidazole compound and method for preparing the same OTSUKA PHARMACEUTICAL CO., LTD. 2008-08-21 US disclosed
US-20080090781-A1 Formulations Containing Alkylphosphocholines Using Novel Negative Charge Carriers MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2008-04-17 US disclosed
EP-1827379-A2 FORMULATIONS CONTAINING ALKYLPHOSPHOCHOLINES USING NOVEL NEGATIVE CHARGE CARRIERS MPG Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2007-09-05 EP disclosed
WO-2006042751-A2 FORMULATIONS CONTAINING ALKYLPHOSPHOCHOLINES USING NOVEL NEGATIVE CHARGE CARRIERS MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2006-04-27 WO disclosed
US-20030199476-A1 Medicament for the stimulation of leucopoiesis and treatment of tumour and protozoan diseases acarinosis and arthropod-borne diseases and a method for production thereof MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2003-10-23 US disclosed
WO-2003028701-A2 LIPOSOMES CONTAINING (ETHER)LYSOLECITHINS MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2003-04-10 WO disclosed
WO-2003028736-A2 PHARMACEUTICAL PREPARATIONS COMPRISING ALKYL PHOSPHOCHOLINE COMPOUNDS IN LIPOSOMES WHICH MAY BE STERILE-FILTERED OR HEAT-STERILISED MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2003-04-10 WO disclosed
EP-1267943-A2 MEDICAMENT FOR THE STIMULATION OF LEUCOPOIESIS AND TREATMENT OF TUMOUR AND PROTOZOAN DISEASES ACARINOSIS AND ARTHROPOD-BORNE DISEASES AND A METHOD FOR PRODUCTION THEREOF Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2003-01-02 EP disclosed
WO-2001072289-A2 MEDICAMENT FOR THE STIMULATION OF LEUCOPOIESIS AND TREATMENT OF TUMOUR AND PROTOZOAN DISEASES ACARINOSIS AND ARTHROPOD-BORNE DISEASES AND A METHOD FOR PRODUCTION THEREOF MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2001-10-04 WO disclosed