⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15046554 | 0.76 | — | — | |
| SCHEMBL1038352 | 0.75 | — | — | |
| SCHEMBL5270227 | 0.75 | — | — | |
| SCHEMBL1887803 | 0.71 | — | — | |
| SCHEMBL19513804 | 0.71 | — | — | |
| SCHEMBL620683 | 0.71 | — | — | |
| SCHEMBL590523 | 0.71 | — | — | |
| SCHEMBL4257130 | 0.71 | — | — | |
| SCHEMBL10967776 | 0.71 | — | — | |
| SCHEMBL21590227 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240425481-A1 | SUBSTITUTED BENZIMIDAZOLES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | EPIGENETIX, INC. | 2024-12-26 | — | — | US | disclosed |
| US-20230257352-A1 | RAF KINASE INHIBITORS AND METHODS OF USE THEREOF | DECIPHERA PHARMACEUTICALS, LLC | 2023-08-17 | — | — | US | disclosed |
| CN-110997656-B | Substituted indole compounds useful as TLR7/8/9 inhibitors | 百时美施贵宝公司 | 2023-04-14 | — | — | CN | disclosed |
| WO-2023009475-A1 | ROCK2 INHIBITORS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-02-02 | — | — | WO | disclosed |
| CN-114605387-A | Substituted benzimidazoles, their preparation and their use as medicaments | 埃皮吉纳提克斯股份有限公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-113939291-A | 1, 8-naphthyridinone compounds and uses thereof | 诺维逊生物股份有限公司 | 2022-01-14 | — | — | CN | disclosed |
| WO-2020150676-A1 | 1,8-NAPHTHYRIDINONE COMPOUNDS AND USES THEREOF | NUVATION BIO INC. (US) | 2020-07-23 | — | — | WO | disclosed |
| EP-3661926-A1 | SUBSTITUTED INDOLE COMPOUNDS USEFUL AS INHIBITORS OF TLR7/8/9 | Bristol-Myers Squibb Company (US) | 2020-06-10 | — | — | EP | disclosed |
| WO-2019028302-A1 | SUBSTITUTED INDOLE COMPOUNDS USEFUL AS INHIBITORS OF TLR7/8/9 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-02-07 | — | — | WO | disclosed |
| US-9861637-B2 | Heterocyclic compounds as bromodomain inhibitors | ZENITH EPIGENETICS LTD. (CA) | 2018-01-09 | — | — | US | disclosed |
| WO-2013185284-A1 | PYRIDINONE AND PYRIDAZINONE DERIVATIVES | ABBOTT LABORATORIES (US) | 2013-12-19 | — | — | WO | disclosed |
| WO-2013188381-A1 | PYRIDINONE AND PYRIDAZINONE DERIVATIVES | ABBVIE INC. (US) | 2013-12-19 | — | — | WO | disclosed |
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |
| US-20100041891-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | US | disclosed |
| CN-1688546-A | Pyridinyl amides and imides for use as fungicides | DU PONT (US) | 2005-10-26 | — | — | CN | disclosed |
| CN-1684946-A | Pyridinyl amides and compositions thereof for use as fungicides | DU PONT (US) | 2005-10-19 | — | — | CN | disclosed |
| US-20050020643-A1 | Pyridinyl amides and compositions thereof for use as fungicides | E.I. DU PONT DE NEMOURS AND COMPANY | 2005-01-27 | — | — | US | disclosed |
| EP-1485355-A2 | PYRIDINYL AMIDES AND COMPOSITIONS THEREOF FOR USE AS FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-12-15 | — | — | EP | disclosed |
| WO-2003080576-A2 | PYRIDINYL AMIDES AND COMPOSITIONS THEREOF FOR USE AS FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-10-02 | — | — | WO | disclosed |