Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TLR2 | O60603 | 1/20 | 0.31 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13056639 | 1.00 | SMN1; SMN2 (0.36) | SMN1; SMN2HPGDHTTMEN1KMT2A | |
| SCHEMBL12197747 | 1.00 | SMN1; SMN2 (0.36) | SMN1; SMN2HPGDHTTMEN1KMT2A | |
| SCHEMBL22202997 | 1.00 | SMN1; SMN2 (0.36) | SMN1; SMN2HPGDHTTMEN1KMT2A | |
| SCHEMBL13248325 | 0.99 | SMN1; SMN2 (0.36) | SMN1; SMN2HPGDHTTMEN1KMT2A | |
| SCHEMBL13248341 | 0.89 | SMN1; SMN2 (0.40) | SMN1; SMN2HPGDHTTKMT2AMTNR1A | |
| SCHEMBL19170723 | 0.89 | SMN1; SMN2 (0.34) | SMN1; SMN2HPGDHTTMEN1KMT2A | |
| SCHEMBL19732577 | 0.89 | SMN1; SMN2 (0.45) | SMN1; SMN2HPGDHTTMEN1KMT2A | |
| SCHEMBL26199214 | 0.88 | SMN1; SMN2 (0.34) | SMN1; SMN2HPGDHTTMEN1KMT2A | |
| SCHEMBL22224280 | 0.88 | SMN1; SMN2 (0.38) | SMN1; SMN2HPGDHTTMEN1KMT2A | |
| SCHEMBL23751331 | 0.87 | SMN1; SMN2 (0.36) | SMN1; SMN2HPGDHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2850061-B1 | HALOGENATED INDOLE DERIVATIVES FOR PHOTODYNAMIC THERAPY | NANOQUANTUM SCIENCES INC (US) | 2020-09-16 | — | — | EP | disclosed |
| US-9839687-B2 | Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule | SUZHOU M-CONJ BIOTECH CO., LTD. (CN) | 2017-12-12 | — | — | US | disclosed |
| US-9572881-B2 | Halogenated compounds for photodynamic therapy | NANOQUANTUM SCIENCES, INC. (US) | 2017-02-21 | — | — | US | disclosed |