Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24801714 | 0.91 | HPGD (0.34) | SMN1; SMN2HPGDHTTMEN1KMT2A | |
| SCHEMBL13056639 | 0.88 | SMN1; SMN2 (0.36) | SMN1; SMN2HPGDHTTMEN1KMT2A | |
| SCHEMBL18532465 | 0.88 | SMN1; SMN2 (0.36) | SMN1; SMN2HPGDHTTMEN1KMT2A | |
| SCHEMBL22202997 | 0.88 | SMN1; SMN2 (0.36) | SMN1; SMN2HPGDHTTMEN1KMT2A | |
| SCHEMBL12197747 | 0.88 | SMN1; SMN2 (0.36) | SMN1; SMN2HPGDHTTMEN1KMT2A | |
| SCHEMBL15699820 | 0.87 | HPGD (0.32) | SMN1; SMN2HPGDHTT | |
| SCHEMBL18929368 | 0.87 | TLR2 (0.38) | HPGDMEN1KMT2ATLR2TLR1 | |
| SCHEMBL25129444 | 0.87 | TLR2 (0.38) | HPGDMEN1KMT2ATLR2TLR1 | |
| SCHEMBL22443641 | 0.87 | TLR2 (0.38) | HPGDMEN1KMT2ATLR2TLR1 | |
| SCHEMBL12317123 | 0.87 | TLR2 (0.38) | HPGDMEN1KMT2ATLR2TLR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020146541-A2 | TRACELESS LINKERS AND PROTEIN-CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2020-07-16 | — | — | WO | disclosed |