SCHEMBL18533016

SCHEMBL18533016

CCCCc1ccc(N(c2ccc(C)cc2)c2ccc(-c3ccc(N(c4ccc(CCCC)cc4)c4ccc(C(C)(C)CCC)cc4)cc3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 4/20 0.48
RARB P10826 6/20 0.39
HSD11B1 P28845 1/20 0.37
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
ATM Q13315 1/20 0.36
NISCH Q9Y2I1 1/20 0.36
TSHR P16473 2/20 0.35
HSD17B10 Q99714 1/20 0.35
TP53 P04637 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CNR1 P21554 2/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
RARA P10276 1/20 0.35
MAPT P10636 1/20 0.35
MTOR P42345 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14228174 0.94 CNR2 (0.46) CNR2RARBHSD11B1NPC1RAB9A
SCHEMBL13425901 0.90 CNR2 (0.43) CNR2RARBHSD11B1NPC1RAB9A
SCHEMBL13425909 0.90 CA2 (0.43) CNR2NPC1RAB9ACA1CA2
SCHEMBL14466891 0.89 CNR2 (0.42) CNR2RARBHSD11B1NPC1RAB9A
SCHEMBL13354844 0.87 CA2 (0.41) CNR2NPC1RAB9ACA1CA2
SCHEMBL18531364 0.87 CA2 (0.41) CNR2NPC1RAB9ACA1CA2
SCHEMBL13434787 0.86 KCNH2 (0.47) CNR2NPC1RAB9ACA1CA2
SCHEMBL2607544 0.85 RARB (0.50) CNR2RARBHSD11B1NPC1RAB9A
SCHEMBL258192 0.85 RARB (0.50) CNR2RARBHSD11B1NPC1RAB9A
SCHEMBL17702098 0.85 RARB (0.50) CNR2RARBHSD11B1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9574084-B2 Hole transport composition E I DU PONT DE NEMOURS AND COMPANY (US) 2017-02-21 US disclosed