Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TACR3 | P29371 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434503 | 0.88 | NPSR1 (0.38) | ADORA2APDE10ANUDT1NPSR1KDM4E | |
| SCHEMBL19289790 | 0.88 | PDE10A (0.38) | ADORA2APDE10ANUDT1NPSR1LMNA | |
| SCHEMBL18533248 | 0.85 | NPSR1 (0.34) | ADORA2APDE10ANUDT1NPSR1KDM4E | |
| SCHEMBL15561446 | 0.84 | ELANE (0.38) | PDE10ANUDT1ALDH1A1DHODHTACR3 | |
| SCHEMBL12697673 | 0.83 | PDE10A (0.44) | ADORA2APDE10ANUDT1KDM4EALDH1A1 | |
| SCHEMBL15561448 | 0.82 | PDE10A (0.43) | ADORA2APDE10ANUDT1LMNADHODH | |
| SCHEMBL15561447 | 0.81 | PDE10A (0.40) | ADORA2APDE10ANUDT1KDM4EALDH1A1 | |
| SCHEMBL28019204 | 0.79 | ADORA2A (0.43) | ADORA2APDE10ANPSR1KDM4EALDH1A1 | |
| SCHEMBL18567245 | 0.79 | PLA2G2A (0.46) | ADORA2APDE10ANPSR1KDM4EALDH1A1 | |
| SCHEMBL18567119 | 0.78 | PLA2G2A (0.40) | ADORA2APDE10AKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2673284-B1 | NEW IRIDIUM-BASED COMPLEXES FOR ECL | ROCHE DIAGNOSTICS GMBH (DE) | 2017-08-30 | — | — | EP | disclosed |
| EP-2882823-B1 | NEW IRIDIUM-BASED COMPLEXES FOR ECL | ROCHE DIAGNOSTICS GMBH (DE) | 2017-02-22 | — | — | EP | disclosed |