Known targets — ChEMBL curated mechanism
SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9A
The experimentally established mechanism targets of Phenazopyridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.82 |
| ▸ | MAPT | P10636 | 8/20 | 0.82 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.82 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.82 |
| ▸ | HBB | P68871 | 2/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.82 |
| ▸ | TSHR | P16473 | 2/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.82 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.82 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.82 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.82 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.79 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.79 |
| ▸ | LMNA | P02545 | 2/20 | 0.79 |
| ▸ | USP2 | O75604 | 1/20 | 0.79 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.79 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.79 |
| ▸ | DRD2 | P14416 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenazopyridine SCHEMBL5948996 | 0.94 | MEN1 (0.77) | MEN1KMT2AMAPTMAPK1TDP1 | |
| Phenazopyridine SCHEMBL270 | 0.94 | MEN1 (0.77) | MEN1KMT2AMAPTMAPK1TDP1 | |
| Phenazopyridine SCHEMBL960940 | 0.92 | MEN1 (0.73) | MEN1KMT2AMAPTMAPK1TDP1 | |
| Phenazopyridine SCHEMBL28796595 | 0.91 | MAPT (1.00) | MEN1KMT2AMAPTMAPK1TDP1 | |
| Phenazopyridine SCHEMBL14687482 | 0.91 | MAPT (1.00) | MEN1KMT2AMAPTMAPK1TDP1 | |
| Phenazopyridine SCHEMBL19357 | 0.91 | MAPT (1.00) | MEN1KMT2AMAPTMAPK1TDP1 | |
| Phenazopyridine SCHEMBL29392321 | 0.91 | MAPT (1.00) | MEN1KMT2AMAPTMAPK1TDP1 | |
| Phenazopyridine SCHEMBL26499 | 0.91 | MAPT (1.00) | MEN1KMT2AMAPTMAPK1TDP1 | |
| Phenazopyridine SCHEMBL215655 | 0.91 | MAPT (1.00) | MEN1KMT2AMAPTMAPK1TDP1 | |
| Phenazopyridine SCHEMBL7406346 | 0.90 | MEN1 (0.71) | MEN1KMT2AMAPTMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025460-A1 | OXADIAZOLINONE DERIVATIVES AND USE THEREOF IN PEST CONTROL | BAYER CROPSCIENCE AG (DE) | 2012-03-01 | — | — | WO | disclosed |