Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 2/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 9/20 | 0.37 |
| ▸ | PPARG | P37231 | 8/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 3/20 | 0.35 |
| ▸ | CTSK | P43235 | 3/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | GNRHR | P30968 | 1/20 | 0.34 |
| ▸ | MDM4 | O15151 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16561823 | 1.00 | ITGA4 (0.38) | ITGA4ITGB7PPARAPPARGACE | |
| SCHEMBL17925379 | 0.91 | GSTP1 (0.36) | ITGA4ITGB7SCDCTSSCTSK | |
| SCHEMBL16561830 | 0.91 | GSTP1 (0.36) | ITGA4ITGB7SCDCTSSCTSK | |
| SCHEMBL17933373 | 0.87 | ITGA4 (0.41) | ITGA4ITGB7PPARAPPARGACE | |
| SCHEMBL15284890 | 0.81 | MDM4 (0.42) | PPARAPPARGACEPPARDCTSS | |
| SCHEMBL882678 | 0.81 | MDM4 (0.42) | PPARAPPARGACEPPARDCTSS | |
| SCHEMBL21315764 | 0.80 | PPARA (0.45) | ITGA4ITGB7PPARAPPARGACE | |
| SCHEMBL16561853 | 0.80 | PPARA (0.45) | ITGA4ITGB7PPARAPPARGACE | |
| SCHEMBL15284771 | 0.79 | ITGA4 (0.40) | ITGA4ITGB7PPARAPPARGACE | |
| SCHEMBL882959 | 0.79 | ITGA4 (0.40) | ITGA4ITGB7PPARAPPARGACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2976346-B1 | PHOSPHOHISTIDINE AND PHOSPHOTYROSINE ANALOGUES | UNIV SHEFFIELD (GB) | 2017-02-22 | — | — | EP | disclosed |