Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16278189 | 0.84 | CYP4F2 (0.46) | HPGDEGFRKMT2AMEN1CYP1A2 | |
| SCHEMBL1524930 | 0.83 | KDM4E (0.42) | HPGDTSHRKMT2AMEN1CYP1A2 | |
| SCHEMBL30094494 | 0.83 | KDM4E (0.42) | HPGDTSHRKMT2AMEN1CYP1A2 | |
| SCHEMBL19900062 | 0.83 | DGAT1 (0.39) | CYP11B1CYP11B2TSHRRAB9ANPC1 | |
| SCHEMBL851581 | 0.82 | MIF (0.44) | CYP11B1CYP11B2TSHRKMT2AKDM4E | |
| SCHEMBL19385660 | 0.81 | CYP11B1 (0.49) | CYP11B1CYP11B2TSHREGFRCYP1A2 | |
| SCHEMBL2786582 | 0.81 | CYP11B1 (0.48) | CYP11B1CYP11B2TSHRKMT2AKDM4E | |
| SCHEMBL15849059 | 0.81 | CYP11B1 (0.48) | CYP11B1CYP11B2KMT2AMEN1KDM4E | |
| SCHEMBL3515895 | 0.80 | FFAR1 (0.55) | HPGDTSHRL3MBTL1RAB9ANPC1 | |
| SCHEMBL25469622 | 0.78 | HTT (0.51) | CYP11B1CYP11B2KMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2976346-B1 | PHOSPHOHISTIDINE AND PHOSPHOTYROSINE ANALOGUES | UNIV SHEFFIELD (GB) | 2017-02-22 | — | — | EP | disclosed |