SCHEMBL1853530

SCHEMBL1853530

C/C=C/C(=O)Oc1c([N+](=O)[O-])cc(C(CCC)CCCC)cc1[N+](=O)[O-]

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.36
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
ESR1 P03372 1/20 0.33
TDP1 Q9NUW8 2/20 0.33
TPMT P51580 1/20 0.32
SMN1; SMN2 Q16637 3/20 0.31
KMT2A Q03164 2/20 0.31
PTGS2 P35354 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
VCAM1 P19320 1/20 0.31
HCAR3 P49019 1/20 0.31
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1853532 1.00 ALDH1A1 (0.36) ALDH1A1GAAMAPTESR1TDP1
SCHEMBL1851745 0.90 ALDH1A1 (0.36) ALDH1A1GAAMAPTESR1TDP1
SCHEMBL1851744 0.90 ALDH1A1 (0.36) ALDH1A1GAAMAPTESR1TDP1
SCHEMBL14510331 0.86 ALDH1A1 (0.40) ALDH1A1GAATDP1TPMTKMT2A
SCHEMBL1851431 0.85 TDP1 (0.46) ALDH1A1GAAMAPTTDP1SMN1; SMN2
SCHEMBL1851428 0.85 TDP1 (0.46) ALDH1A1GAAMAPTTDP1SMN1; SMN2
SCHEMBL27686380 0.84 TDP1 (0.37) ALDH1A1GAAMAPTESR1TDP1
SCHEMBL11383850 0.83 TDP1 (0.40) ALDH1A1GAAMAPTESR1TDP1
SCHEMBL1855877 0.83 ESR1 (0.37) ALDH1A1GAAMAPTESR1TDP1
SCHEMBL1855881 0.83 ESR1 (0.37) ALDH1A1GAAMAPTESR1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8557866-B2 Isomeric mixtures of dinitro-octylphenyl esters and synergistic fungicidal mixtures therefrom DOW AGROSCIENCES, LLC. (US) 2013-10-15 US disclosed
EP-1830641-B1 ISOMERIC MIXTURES OF DINITRO-OCTYLPHENYL ESTERS AND SYNERGISTIC FUNGICIDAL MIXTURES THEREFROM DOW AGROSCIENCES LLC (US) 2011-05-25 EP disclosed
US-20080255233-A1 Isomeric mixtures of dinitro-octylphenyl esters and synergistic fungicidal mixtures therefrom DOW AGROSCIENCES LLC (US) 2008-10-16 US disclosed
EP-1830641-A1 ISOMERIC MIXTURES OF DINITRO-OCTYLPHENYL ESTERS AND SYNERGISTIC FUNGICIDAL MIXTURES THEREFROM Dow AgroSciences LLC (US) 2007-09-12 EP disclosed
WO-2006044460-A1 ISOMERIC MIXTURES OF DINITRO-OCTYLPHENYL ESTERS AND SYNERGISTIC FUNGICIDAL MIXTURES THEREFROM DOW AGROSCIENCES LLC (US) 2006-04-27 WO disclosed