Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.55 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.55 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.55 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.55 |
| ▸ | ADK | P55263 | 6/20 | 0.50 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18009754 | 1.00 | PI4KA (0.55) | PI4KAPI4K2BPI4K2API4KBADK | |
| SCHEMBL18026249 | 0.91 | PI4KA (0.44) | PI4KAPI4K2BPI4K2API4KBADK | |
| SCHEMBL18009847 | 0.88 | PI4KA (0.56) | PI4KAPI4K2BPI4K2API4KBADK | |
| SCHEMBL18572215 | 0.88 | PI4KA (0.56) | PI4KAPI4K2BPI4K2API4KBADK | |
| SCHEMBL31526134 | 0.88 | PI4KA (0.66) | PI4KAPI4K2BPI4K2API4KBADK | |
| SCHEMBL16120836 | 0.88 | PI4KA (0.55) | PI4KAPI4K2BPI4K2API4KBADK | |
| SCHEMBL90990 | 0.88 | ADK (0.67) | PI4KAPI4K2BPI4K2API4KBADK | |
| SCHEMBL67029 | 0.88 | ADK (0.67) | PI4KAPI4K2BPI4K2API4KBADK | |
| SCHEMBL29772297 | 0.88 | PI4KA (0.55) | PI4KAPI4K2BPI4K2API4KBADK | |
| SCHEMBL60684 | 0.88 | ADK (0.67) | PI4KAPI4K2BPI4K2API4KBADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3133080-A1 | NOVEL CYTOSTATIC 7-DEAZAPURINE NUCLEOSIDES | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 2017-02-22 | — | — | EP | disclosed |