Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 19/20 | 0.91 |
| ▸ | F11 | P03951 | 19/20 | 0.91 |
| ▸ | KLKB1 | P03952 | 19/20 | 0.91 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18536239 | 0.95 | KLKB1 (1.00) | F9F11KLKB1 | |
| SCHEMBL15594105 | 0.95 | KLKB1 (1.00) | F9F11KLKB1 | |
| SCHEMBL15594144 | 0.92 | F9 (1.00) | F9F11KLKB1 | |
| SCHEMBL18536152 | 0.92 | F9 (1.00) | F9F11KLKB1 | |
| SCHEMBL15594205 | 0.90 | KLKB1 (1.00) | F9F11KLKB1 | |
| SCHEMBL18536240 | 0.90 | KLKB1 (1.00) | F9F11KLKB1 | |
| SCHEMBL18523890 | 0.89 | F9 (0.91) | F9F11KLKB1 | |
| SCHEMBL15594146 | 0.87 | KLKB1 (1.00) | F9F11KLKB1 | |
| SCHEMBL18535945 | 0.87 | KLKB1 (1.00) | F9F11KLKB1 | |
| SCHEMBL15594135 | 0.87 | F11 (1.00) | F9F11KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2880026-B1 | DIHYDROPYRIDONE P1 AS FACTOR XIA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-02-22 | — | — | EP | disclosed |