Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2067359 | 1.00 | HTR2B (0.41) | HTR2BUSP30HCRTR1HCRTR2 | |
| SCHEMBL13962627 | 0.89 | HTR2B (0.43) | HTR2BUSP30 | |
| Trifluoroacetic Acid SCHEMBL2067634 | 0.88 | HTR2B (0.49) | HTR2B | |
| Trifluoroacetic Acid SCHEMBL2068117 | 0.87 | NPC1 (0.46) | HTR2BUSP30 | |
| SCHEMBL9970053 | 0.86 | HTR2B (0.55) | HTR2B | |
| Trifluoroacetic Acid SCHEMBL2066884 | 0.85 | EPHX2 (0.45) | HTR2BHCRTR1HCRTR2 | |
| SCHEMBL14899096 | 0.85 | HTR2B (0.41) | HTR2BUSP30 | |
| SCHEMBL9970063 | 0.85 | NPC1 (0.52) | USP30 | |
| SCHEMBL9970061 | 0.83 | EPHX2 (0.48) | HTR2B | |
| SCHEMBL13949588 | 0.83 | USP14 (0.42) | HTR2BUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170860-B9 | BENZIMIDAZOLE DERIVATIVES | PFIZER (US) | 2017-02-22 | — | — | EP | disclosed |