Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.50 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2068031 | 1.00 | MTOR (0.52) | MTOREPHX2CACNA1GCACNA1BKCNH2 | |
| Hydrochloric Acid SCHEMBL2067983 | 0.99 | MTOR (0.52) | MTOREPHX2CACNA1GCACNA1BKCNH2 | |
| SCHEMBL2068332 | 0.90 | NPC1 (0.47) | EPHX2 | |
| SCHEMBL18536579 | 0.90 | NPC1 (0.47) | EPHX2 | |
| SCHEMBL18536617 | 0.90 | MTOR (0.43) | MTOREPHX2CACNA1GCACNA1BKCNH2 | |
| SCHEMBL9970011 | 0.89 | NPC1 (0.44) | — | |
| Hydrochloric Acid SCHEMBL2067434 | 0.89 | NPC1 (0.46) | EPHX2 | |
| SCHEMBL18536590 | 0.89 | EPHX2 (0.49) | MTOREPHX2 | |
| SCHEMBL13962125 | 0.89 | EPHX2 (0.49) | MTOREPHX2 | |
| SCHEMBL9970048 | 0.89 | EPHX2 (0.51) | EPHX2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170860-B9 | BENZIMIDAZOLE DERIVATIVES | PFIZER (US) | 2017-02-22 | — | — | EP | disclosed |