Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 17/20 | 0.59 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18536731 | 0.92 | ENPP2 (0.69) | ENPP2 | |
| SCHEMBL15874887 | 0.91 | ENPP2 (0.57) | ENPP2DDB1CRBNMAPK1 | |
| SCHEMBL15874908 | 0.88 | ENPP2 (0.54) | ENPP2DDB1CRBNMAPK1 | |
| SCHEMBL18536835 | 0.87 | ENPP2 (0.56) | ENPP2DDB1CRBNMAPK1CDK1 | |
| SCHEMBL19001278 | 0.86 | ENPP2 (0.68) | ENPP2DDB1CRBNMAPK1 | |
| SCHEMBL15875461 | 0.84 | ENPP2 (0.69) | ENPP2DDB1CRBNMAPK1 | |
| SCHEMBL15875635 | 0.84 | ENPP2 (0.55) | ENPP2DDB1CRBN | |
| SCHEMBL15875522 | 0.84 | ENPP2 (0.69) | ENPP2 | |
| SCHEMBL16474045 | 0.84 | ENPP2 (0.51) | ENPP2DDB1CRBNMAPK1 | |
| SCHEMBL15883204 | 0.84 | ENPP2 (0.69) | ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2943494-B1 | PYRIDO- OR PYRROLO-FUSED PYRIMIDINE DERIVATIVES AS AUTOTAXIN INHIBITORS FOR TREATING PAIN | LILLY CO ELI (US) | 2017-02-22 | — | — | EP | disclosed |