Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | S100B | P04271 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2161113 | 0.89 | ADORA3 (0.38) | ADORA3ADORA2AADORA2BADORA1SKP2 | |
| SCHEMBL2161791 | 0.88 | SKP2 (0.40) | ADORA3ADORA2AADORA2BADORA1SKP2 | |
| SCHEMBL2161804 | 0.88 | ADORA3 (0.37) | ADORA3ADORA2AADORA2BADORA1SKP2 | |
| SCHEMBL1833654 | 0.86 | ADORA3 (0.36) | ADORA3ADORA2AADORA2BADORA1SKP2 | |
| SCHEMBL1833890 | 0.85 | ADORA3 (0.36) | ADORA3ADORA2AADORA2BADORA1SKP2 | |
| SCHEMBL1833243 | 0.84 | ADORA3 (0.35) | ADORA3ADORA2AADORA2BADORA1SKP2 | |
| SCHEMBL2162346 | 0.84 | ADORA3 (0.35) | ADORA3ADORA2AADORA2BADORA1SKP2 | |
| SCHEMBL1836471 | 0.84 | ADORA3 (0.35) | ADORA3ADORA2AADORA2BADORA1SKP2 | |
| SCHEMBL1834307 | 0.83 | SMN1; SMN2 (0.44) | ADORA3ADORA2AADORA2BADORA1POLB | |
| SCHEMBL2161309 | 0.83 | ADORA3 (0.35) | ADORA3ADORA2AADORA2BADORA1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2318374-A2 | INSECTICIDAL BENZENEDICARBOXAMIDE DERIVATIVE | Bayer CropScience AG (DE) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010012442-A2 | INSECTICIDAL BENZENEDICARBOXAMIDE DERIVATIVE | BAYER CROPSCIENCE AG (DE) | 2010-02-04 | — | — | WO | disclosed |