SCHEMBL18537682

SCHEMBL18537682

O=C1C[C@H]2C(=O)OC(=O)CC2C(=O)O1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
ALDH1A1 P00352 1/20 0.32
FNTA P49354 1/20 0.32
PGGT1B P53609 1/20 0.32
KDM4E B2RXH2 1/20 0.31
GMNN O75496 1/20 0.31
PPM1B O75688 1/20 0.31
LMNA P02545 1/20 0.31
PPP1CC P36873 1/20 0.31
TFPI2 P48307 1/20 0.31
RAB9A P51151 1/20 0.31
PPP5C P53041 1/20 0.31
PPP1CA P62136 1/20 0.31
PMP22 Q01453 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
TP53 P04637 1/20 0.31
CYP2D6 P10635 1/20 0.31
NFKB1 P19838 1/20 0.31
THPO P40225 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL114258 1.00 TSHR (0.35) TSHRSMN1; SMN2ALDH1A1FNTAPGGT1B
SCHEMBL15786373 1.00 TSHR (0.35) TSHRSMN1; SMN2ALDH1A1FNTAPGGT1B
SCHEMBL18807102 1.00 TSHR (0.35) TSHRSMN1; SMN2ALDH1A1FNTAPGGT1B
SCHEMBL15780501 1.00 TSHR (0.35) TSHRSMN1; SMN2ALDH1A1FNTAPGGT1B
SCHEMBL18179366 0.85 PLAU (0.33)
SCHEMBL21309109 0.85
SCHEMBL22130004 0.85 SMN1; SMN2 (0.37) TSHRSMN1; SMN2ALDH1A1FNTAPGGT1B
SCHEMBL21309105 0.85
SCHEMBL16237581 0.85 ALDH1A1 (0.30) ALDH1A1
SCHEMBL21241533 0.84 TSHR (0.35) TSHRSMN1; SMN2KDM4EGMNNPPM1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3179303-A1 LIQUID CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2017-06-14 EP disclosed
EP-3163368-A1 LIQUID CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2017-05-03 EP disclosed
EP-3133136-A1 LIQUID CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2017-02-22 EP disclosed