SCHEMBL1854004

SCHEMBL1854004

CC(=O)C1=C[N]N=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1196354 0.77
SCHEMBL3010137 0.70 CYP1A2 (0.43)
SCHEMBL21407345 0.70 APOBEC3A (0.39)
SCHEMBL3296850 0.65
SCHEMBL1400104 0.58
SCHEMBL536432 0.52
Acetone SCHEMBL27547266 0.51
Acetone SCHEMBL4106301 0.51
SCHEMBL7269156 0.50 SMN1; SMN2 (0.60)
SCHEMBL11321959 0.50 SMN1; SMN2 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2324016-B1 3-(N-HETEROCYCLYL)-PYRROLIDINYL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS FERRER INT (ES) 2012-04-25 EP claimed
JP-2011526590-A 2011-10-13 JP claimed
US-20110136829-A1 3-(N-HETEROCYCLYL)-PYRROLIDINYL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS FERRER INTERNACIONAL, S.A. (ES) 2011-06-09 US claimed
EP-2324016-A1 3-(N-HETEROCYCLYL)-PYRROLIDINYL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS Ferrer Internacional, S.A. (ES) 2011-05-25 EP claimed
WO-2010000704-A1 3-(N-HETEROCYCLYL)-PYRROLIDINYL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS FERRER INTERNACIONAL, S.A. (ES) 2010-01-07 WO claimed
EP-2141162-A1 3-(n-heterocyclyl)-pyrrolidinyl-phenyl-oxazolidinones as antibacterial agents Ferrer Internacional, S.A. (ES) 2010-01-06 EP claimed
EP-2324016-B1 3-(N-HETEROCYCLYL)-PYRROLIDINYL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS FERRER INT (ES) 2012-04-25 EP disclosed
US-20110136829-A1 3-(N-HETEROCYCLYL)-PYRROLIDINYL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS FERRER INTERNACIONAL, S.A. (ES) 2011-06-09 US disclosed
EP-2324016-A1 3-(N-HETEROCYCLYL)-PYRROLIDINYL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS Ferrer Internacional, S.A. (ES) 2011-05-25 EP disclosed
WO-2010000704-A1 3-(N-HETEROCYCLYL)-PYRROLIDINYL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS FERRER INTERNACIONAL, S.A. (ES) 2010-01-07 WO disclosed
EP-2141162-A1 3-(n-heterocyclyl)-pyrrolidinyl-phenyl-oxazolidinones as antibacterial agents Ferrer Internacional, S.A. (ES) 2010-01-06 EP disclosed