SCHEMBL7269156

SCHEMBL7269156

CC(=O)c1cc(C(C)=O)c(C(C)=O)cc1C(C)=O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.60
KDM4E B2RXH2 3/20 0.48
HTT P42858 2/20 0.44
CA5A P35218 1/20 0.43
CYP3A4 P08684 4/20 0.42
TSHR P16473 1/20 0.42
MEN1 O00255 3/20 0.41
HPGD P15428 3/20 0.41
KMT2A Q03164 3/20 0.41
POLB P06746 2/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPK1 P28482 1/20 0.41
NSD2 O96028 1/20 0.41
MAPT P10636 1/20 0.41
MCL1 Q07820 1/20 0.41
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39
NPC1 O15118 1/20 0.38
GAA P10253 1/20 0.38
CYP1A2 P05177 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13085841 0.87 SMN1; SMN2 (0.50) SMN1; SMN2KDM4EHTTMEN1KMT2A
SCHEMBL12927387 0.87 SMN1; SMN2 (0.50) SMN1; SMN2KDM4EHTTMEN1KMT2A
SCHEMBL11940936 0.87 SMN1; SMN2 (0.50) SMN1; SMN2KDM4EHTTMEN1KMT2A
SCHEMBL14013046 0.86 SMN1; SMN2 (0.55) SMN1; SMN2KDM4EHTTCA5ACYP3A4
SCHEMBL13837953 0.85 SMN1; SMN2 (0.48) SMN1; SMN2KDM4EHTTCA5ACYP3A4
SCHEMBL14852670 0.85 SMN1; SMN2 (0.48) SMN1; SMN2KDM4EHTTCYP3A4TSHR
SCHEMBL14436800 0.81 SMN1; SMN2 (0.56) SMN1; SMN2KDM4EHTTCA5ACYP3A4
SCHEMBL7262130 0.81 SMN1; SMN2 (0.50) SMN1; SMN2KDM4EHTTCA5ACYP3A4
SCHEMBL26053946 0.81 BRD4 (0.44) SMN1; SMN2KDM4EHTTCA5ACYP3A4
SCHEMBL1258995 0.81 HTT (0.60) SMN1; SMN2KDM4EHTTCA5ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6583229-B2 Core layer is formed by vulcanizing and press molding a rubber composition of a base rubber, crosslinking agent, organic peroxide, filler, and a benzene mercaptan, polysufide, or metal sulfide; exceptional rebound, flight, shot feel SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-06-24 US claimed
US-20240190899-A1 ORGANIC COMPOUND, OPTO-ELECTRONIC DEVICE, ELECTRONIC APPARATUS, AND ELECTRONIC DEVICE SAMSUNG DISPLAY CO LTD (KR) 2024-06-13 US disclosed
US-11535703-B2 Methanesulfonic acid mediated solvent free synthesis of conjugated porous polymer networks THE TEXAS A&M UNIVERSITY SYSTEM (US) 2022-12-27 US disclosed
EP-3919457-A1 GLASS ARTICLES WITH LOW-FRICTION COATINGS Corning Incorporated (US) 2021-12-08 EP disclosed
US-20210230359-A1 Methanesulfonic Acid Mediated Solvent Free Synthesis of Conjugated Porous Polymer Networks THE TEXAS A&M UNIVERSITY SYSTEM 2021-07-29 US disclosed
US-20190210768-A1 DELAMINATION RESISTANT GLASS CONTAINERS WITH HEAT-TOLERANT COATINGS CORNING INCORPORATED (US) 2019-07-11 US disclosed
US-10307334-B2 Glass containers with delamination resistance and improved damage tolerance CORNING INCORPORATED (US) 2019-06-04 US disclosed
US-20190076331-A1 GLASS ARTICLES WITH LOW-FRICTION COATINGS CORNING INCORPORATED (US) 2019-03-14 US disclosed
US-20180149975-A1 NEGATIVE TYPE PHOTOSENSITIVE RESIN COMPOSITION, NEGATIVE TYPE PLANOGRAPHIC PRINTING PLATE PRECURSOR, AND METHOD OF PREPARING PLANOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2018-05-31 US disclosed
US-20170334604-A1 DELAMINATION RESISTANT GLASS CONTAINERS WITH HEAT-TOLERANT COATINGS CORNING INCORPORATED (US) 2017-11-23 US disclosed
US-20100068642-A1 Universal Stir-In Pigments CLARIANT FINANCE (BVI) LIMITED (VG) 2010-03-18 US disclosed
US-20100068642-A1 Universal Stir-In Pigments CLARIANT FINANCE (BVI) LIMITED (VG) 2010-03-18 US disclosed
WO-2010008214-A2 COPPER FOIL FOR PRINTED CIRCUIT BOARD, METHOD OF PREPARING THE SAME, AND FLEXIBLE COPPER CLAD LAMINATE USING POLYAMIC ACID PRECURSOR AND COPPER FOIL ILJIN COPPER FOIL CO., LTD. (KR) 2010-01-21 WO disclosed
US-20090274947-A1 Imidazolidinone nitroxides as electrode materials for energy storage devices CIBA CORP. 2009-11-05 US disclosed
WO-2008055566-A2 UNIVERSAL STIR-IN PIGMENTS CLARIANT FINANCE (BVI) LIMITED (VG) 2008-05-15 WO disclosed
US-20080107986-A1 Charge controlling agent for electrophotographic toners, electrophotographic developers, powder coatings, electret materials, electronic inks, electronic papers and in electrostatic separation operations comprising a hydrophobic salt-like structured silicate MICHEL EDUARD 2008-05-08 US disclosed
WO-2008031733-A2 IMIDAZOLIDINONE NITROXIDES AS ELECTRODE MATERIALS FOR ENERGY STORAGE DEVICES CIBA HOLDING INC. (CH) 2008-03-20 WO disclosed
US-7309558-B1 Use of salt-like structured silicas as charge control agents CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2007-12-18 US disclosed
US-7179401-B2 Thermotropic liquid-crystalline polymer KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 2007-02-20 US disclosed
US-4560740-A QUINONE COMPOUNDS AND/OR COMPLEXES ANHYDRIDES OR REACTION PRODUCT; CROSSLINKING SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090274947-A1 Imidazolidinone nitroxides as electrode materials for energy storage devices IDH2, NQO1, NOX1 SMN1; SMN2 1835/4885KDM4E 253/4885HTT 3495/4885
US-20240190899-A1 ORGANIC COMPOUND, OPTO-ELECTRONIC DEVICE, ELECTRONIC APPARATUS, AND ELECTRONIC DEVICE CYBB, CYBA, PPOX SMN1; SMN2 4471/4885KDM4E 3627/4885HTT 4581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.