Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.41 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18540053 | 0.95 | THRB (0.49) | THRBMAPTPARP10SMN1; SMN2TP53 | |
| SCHEMBL9305285 | 0.94 | PARP10 (0.50) | THRBMAPTPARP10KMT2AALDH1A1 | |
| SCHEMBL8912455 | 0.94 | PARP10 (0.50) | THRBMAPTPARP10KMT2AALDH1A1 | |
| SCHEMBL18540075 | 0.94 | THRB (0.47) | THRBMAPTPARP10SMN1; SMN2TP53 | |
| SCHEMBL18540263 | 0.91 | THRB (0.42) | THRBMAPTPARP10SMN1; SMN2TP53 | |
| SCHEMBL18540251 | 0.91 | THRB (0.42) | THRBMAPTPARP10SMN1; SMN2TP53 | |
| SCHEMBL18540162 | 0.89 | THRB (0.40) | THRBMAPTPARP10SMN1; SMN2TP53 | |
| SCHEMBL8913348 | 0.88 | THRB (0.61) | THRBMAPTPARP10SMN1; SMN2PRSS1 | |
| SCHEMBL9303442 | 0.88 | KMT2A (0.49) | THRBMAPTPARP10SMN1; SMN2PRSS1 | |
| SCHEMBL8913018 | 0.88 | KMT2A (0.56) | THRBMAPTSMN1; SMN2TP53PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170051206-A1 | LIQUID CRYSTAL COMPOUND HAVING ALKENYL ON BOTH ENDS, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2017-02-23 | — | — | US | disclosed |
| US-20170051206-A1 | LIQUID CRYSTAL COMPOUND HAVING ALKENYL ON BOTH ENDS, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2017-02-23 | — | — | US | disclosed |