SCHEMBL18540430

SCHEMBL18540430

c1cncc(N(c2ccc3ccc4c(N(c5cccnc5)c5cccc6c5oc5ccccc56)ccc5ccc2c3c54)c2cccc3c2oc2ccccc23)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.34
KDM4E B2RXH2 4/20 0.34
HSD17B10 Q99714 4/20 0.34
HPGD P15428 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
TP53 P04637 1/20 0.34
POLB P06746 1/20 0.34
ALOX15 P16050 1/20 0.34
NFKB1 P19838 1/20 0.34
NFKB2 Q00653 1/20 0.34
RELA Q04206 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
PRKDC P78527 5/20 0.34
JAK2 O60674 1/20 0.34
ZAP70 P43403 1/20 0.34
SYK P43405 1/20 0.34
ALDH1A1 P00352 5/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
NAMPT P43490 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18798576 0.87 ALOX5 (0.34) KDM4EHSD17B10HPGDTDP1JAK2
SCHEMBL2515170 0.87 ALOX5 (0.34) KDM4EHSD17B10HPGDTDP1JAK2
SCHEMBL12206533 0.84 CYP1A2 (0.36) KDM4EHSD17B10HPGDTDP1JAK2
SCHEMBL4083821 0.84 ALOX5 (0.37) MAPTKDM4EHSD17B10HPGDTDP1
SCHEMBL18798592 0.84 ALOX5 (0.37) MAPTKDM4EHSD17B10HPGDTDP1
SCHEMBL17222497 0.83 ALOX5 (0.33) KDM4EHSD17B10HPGDTDP1JAK2
SCHEMBL17933051 0.82 TDP1 (0.33) MAPTKDM4EHPGDTDP1ALDH1A1
SCHEMBL22860975 0.82 JAK2 (0.33) MAPTKDM4EHPGDSMN1; SMN2POLB
SCHEMBL20696442 0.81 CYP1A2 (0.39) MAPTKDM4EHSD17B10HPGDTDP1
SCHEMBL24425487 0.81 ALOX5 (0.34) TDP1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230225200-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-13 US disclosed
US-20230225200-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-13 US disclosed
US-11672173-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-06 US disclosed
US-11672173-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-06 US disclosed
US-11211564-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2021-12-28 US disclosed
US-9960361-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-01 US disclosed
US-9960361-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-01 US disclosed
US-20170054081-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-02-23 US disclosed
US-20170054081-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-02-23 US disclosed