Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.33 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GRK6 | P43250 | 1/20 | 0.31 |
| ▸ | TYMP | P19971 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18540468 | 0.93 | SERPINE1 (0.34) | MAPTSERPINE1PLA2G1BATG4BALDH1A1 | |
| SCHEMBL17213068 | 0.93 | TYMP (0.39) | MAPTSERPINE1FAAHPLA2G1BATG4B | |
| SCHEMBL18540469 | 0.90 | PRKAG1 (0.36) | MAPTPLA2G1BATG4BALDH1A1MEN1 | |
| SCHEMBL17213141 | 0.86 | TYMP (0.38) | MAPTSERPINE1PLA2G1BATG4BCYP2C19 | |
| SCHEMBL18540484 | 0.83 | AR (0.35) | MAPTPLA2G1BATG4BALDH1A1CYP1A2 | |
| SCHEMBL18540482 | 0.83 | MEN1 (0.40) | MAPTPLA2G1BATG4BALDH1A1MEN1 | |
| SCHEMBL17212979 | 0.82 | TYMP (0.40) | MAPTPLA2G1BATG4BALDH1A1CYP2C19 | |
| SCHEMBL18540491 | 0.82 | MAPT (0.39) | MAPTPLA2G1BATG4BALDH1A1MEN1 | |
| SCHEMBL18540479 | 0.81 | CYP19A1 (0.48) | MAPTPLA2G1BATG4BALDH1A1MEN1 | |
| SCHEMBL18540579 | 0.80 | MAPT (0.35) | MAPTPLA2G1BATG4BALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170050939-A1 | SMALL MOLECULE INHIBITORS OF G PROTEIN COUPLED RECEPTOR 6 KINASE POLYPEPTIDES | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2017-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170050939-A1 | SMALL MOLECULE INHIBITORS OF G PROTEIN COUPLED RECEPTOR 6 KINASE POLYPEPTIDES | GRK6, GRK2, GRK3 | MAPT 4031/4885SERPINE1 1855/4885FAAH 3137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.