Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.41 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14513402 | 0.86 | KMT2A (0.53) | KMT2AHTTATMTSHRCYP1A2 | |
| SCHEMBL7207304 | 0.86 | KMT2A (0.53) | KMT2AHTTATMTSHRCYP1A2 | |
| SCHEMBL29706360 | 0.86 | KMT2A (0.53) | KMT2AHTTATMTSHRCYP1A2 | |
| SCHEMBL7207300 | 0.86 | KMT2A (0.53) | KMT2AHTTATMTSHRCYP1A2 | |
| SCHEMBL7204422 | 0.85 | KMT2A (0.59) | KMT2AHTTATMTSHRCYP1A2 | |
| SCHEMBL7204429 | 0.85 | KMT2A (0.59) | KMT2AHTTATMTSHRCYP1A2 | |
| SCHEMBL8205498 | 0.76 | MMP9 (0.43) | KMT2ACAPN1 | |
| SCHEMBL7211686 | 0.76 | MMP9 (0.43) | KMT2ACAPN1 | |
| SCHEMBL14123190 | 0.74 | KMT2A (0.48) | KMT2AHTTATMMAPTSMN1; SMN2 | |
| SCHEMBL14123310 | 0.74 | KMT2A (0.48) | KMT2AHTTATMMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017030983-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF CATHEPSINS | MATEON THERAPEUTICS, INC. (US) | 2017-02-23 | — | — | WO | disclosed |