Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 5/20 | 0.59 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.36 |
| ▸ | FYN | P06241 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3197821 | 0.97 | GPR52 (0.62) | GPR52MRGPRX4KDM4EALDH1A1HPGD | |
| SCHEMBL1850137 | 0.87 | GPR52 (0.69) | GPR52HPGDS1PR4S1PR5RAB9A | |
| SCHEMBL1852312 | 0.83 | GPR52 (0.69) | GPR52KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1854620 | 0.82 | GPR52 (0.62) | GPR52MRGPRX4S1PR4S1PR5 | |
| SCHEMBL1848618 | 0.80 | GPR52 (0.77) | GPR52MRGPRX4KDM4EALDH1A1HPGD | |
| SCHEMBL1851711 | 0.79 | GPR52 (0.73) | GPR52KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3209427 | 0.79 | GPR52 (0.71) | GPR52HPGDS1PR4S1PR5 | |
| SCHEMBL1850988 | 0.79 | GPR52 (0.68) | GPR52HPGDS1PR4S1PR5RAB9A | |
| SCHEMBL3222989 | 0.79 | GPR52 (0.76) | GPR52MRGPRX4ALDH1A1S1PR4S1PR5 | |
| SCHEMBL1854490 | 0.78 | GPR52 (0.77) | GPR52S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |