Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 9/20 | 1.00 |
| ▸ | ADRA1A | P35348 | 8/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 7/20 | 1.00 |
| ▸ | ADRA2C | P18825 | 6/20 | 1.00 |
| ▸ | ADRA2B | P18089 | 5/20 | 1.00 |
| ▸ | ADRA1B | P35368 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 1.00 |
| ▸ | ADRA1D | P25100 | 3/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 3/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | HTR1A | P08908 | 2/20 | 1.00 |
| ▸ | THRB | P10828 | 2/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 1.00 |
| ▸ | HTR1B | P28222 | 2/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Rauwolscine SCHEMBL12648480 | 1.00 | ADRA2A (1.00) | ADRA2AADRA1ACYP2D6ADRA2CADRA2B | |
| Rauwolscine SCHEMBL4548294 | 1.00 | ADRA2A (1.00) | ADRA2AADRA1ACYP2D6ADRA2CADRA2B | |
| Rauwolscine SCHEMBL8366111 | 1.00 | ADRA2A (1.00) | ADRA2AADRA1ACYP2D6ADRA2CADRA2B | |
| Rauwolscine SCHEMBL7945869 | 1.00 | ADRA2A (1.00) | ADRA2AADRA1ACYP2D6ADRA2CADRA2B | |
| Rauwolscine SCHEMBL25366080 | 1.00 | ADRA2A (1.00) | ADRA2AADRA1ACYP2D6ADRA2CADRA2B | |
| Rauwolscine SCHEMBL6700479 | 1.00 | ADRA2A (1.00) | ADRA2AADRA1ACYP2D6ADRA2CADRA2B | |
| Rauwolscine SCHEMBL23244673 | 1.00 | ADRA2A (1.00) | ADRA2AADRA1ACYP2D6ADRA2CADRA2B | |
| Rauwolscine SCHEMBL564021 | 1.00 | ADRA2A (1.00) | ADRA2AADRA1ACYP2D6ADRA2CADRA2B | |
| Rauwolscine SCHEMBL22703462 | 1.00 | ADRA2A (1.00) | ADRA2AADRA1ACYP2D6ADRA2CADRA2B | |
| Rauwolscine SCHEMBL244514 | 1.00 | ADRA2A (1.00) | ADRA2AADRA1ACYP2D6ADRA2CADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017031319-A1 | NORADRENERGIC DRUG TREATMENT OF OBSTRUCTIVE SLEEP APNEA | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-02-23 | — | — | WO | disclosed |