Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.35 |
| ▸ | HRH1 | P35367 | 4/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.32 |
| ▸ | HRH2 | P25021 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4606399 | 0.75 | APLNR (0.50) | HRH4HRH1TAAR1HRH3HRH2 | |
| SCHEMBL2002429 | 0.75 | TAAR1 (0.41) | HRH4HRH1TAAR1HRH3HRH2 | |
| SCHEMBL9999635 | 0.75 | HRH4 (0.45) | HRH4HRH1TAAR1HRH3HRH2 | |
| Hydrochloric Acid SCHEMBL1396035 | 0.73 | APLNR (0.48) | HRH4HRH1TAAR1HRH3HRH2 | |
| SCHEMBL15332698 | 0.71 | HRH1 (0.33) | HRH4HRH1HRH3HRH2TSHR | |
| SCHEMBL1086870 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL29956780 | 0.70 | HRH4 (0.32) | HRH4HRH1HRH3HRH2APEX1 | |
| SCHEMBL22265138 | 0.70 | TAAR1 (0.47) | HRH4HRH1TAAR1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL35210959 | 0.69 | HRH1 (0.50) | HRH4HRH1TAAR1HRH3HRH2 | |
| Hydrochloric Acid SCHEMBL3888095 | 0.69 | HRH1 (0.50) | HRH4HRH1TAAR1HRH3HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017029602-A2 | COMPOUNDS FOR USE IN ANTIBACTERIAL APPLICATIONS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-02-23 | — | — | WO | disclosed |