Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 3/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.36 |
| ▸ | CSF1R | P07333 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18544272 | 0.87 | KCNH2 (0.39) | MAP4K4KCNH2 | |
| SCHEMBL2821252 | 0.83 | PDGFRB (0.36) | PDGFRBPDGFRACSF1RNPC1HTT | |
| SCHEMBL3346945 | 0.82 | ERN1 (0.44) | PDGFRBPDGFRACSF1RNPC1HTT | |
| SCHEMBL3345811 | 0.82 | KCNH2 (0.36) | PDGFRBPDGFRACSF1RNPC1HTT | |
| SCHEMBL18544269 | 0.81 | CSF1R (0.36) | PDGFRBPDGFRACSF1RNPC1HTT | |
| SCHEMBL18544276 | 0.80 | PDGFRB (0.36) | PDGFRBPDGFRACSF1RNPC1HTT | |
| SCHEMBL22996915 | 0.80 | KCNH2 (0.37) | PDGFRBPDGFRACSF1RKCNH2 | |
| SCHEMBL20687532 | 0.80 | PDGFRB (0.34) | PDGFRBPDGFRACSF1RNPC1HTT | |
| SCHEMBL14993933 | 0.78 | CSF1R (0.33) | PDGFRBPDGFRACSF1RNPC1HTT | |
| SCHEMBL2169114 | 0.78 | ERN1 (0.41) | PDGFRBPDGFRACSF1RNPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017029602-A2 | COMPOUNDS FOR USE IN ANTIBACTERIAL APPLICATIONS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-02-23 | — | — | WO | disclosed |